Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

bwa aln -m maximum entries in the queue not documented in manual #394

Open
marykthompson opened this issue Jun 7, 2023 · 0 comments
Open

Comments

@marykthompson
Copy link

What is the meaning of the -m option for bwa aln? It is only described at the command line as 'maximum entries in the queue', but I cannot find any description of it in the BWA manual to explain what it does. How would changing this parameter from the default affect my results? I want to be sure to find all matches between my query and the genome up to a given edit distance.

Specifically, let's say that I want to find all matches to my query with up to 2 mismatches in a very large genome. How do I know if I have set this -m option high enough to guarantee that all of those matches are found? If I am finding results with 3 mismatches output at a given -m value, does that mean that all alignments with up to 2 mismatches have definitely been found?

I found this question on the mailing list, but without an answer, so I decided to try here. It might be nice to add this to the manual in the future. Thanks.

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Labels
None yet
Projects
None yet
Development

No branches or pull requests

1 participant